THE ULTIMATE GUIDE TO AHU'S

Approximately 80% of TTP is brought on by deficient action of ADAMTS13. ADAMTS13 deficiency is usually constitutive, because of biallelic ADAMTS13 pathogenic variants; or acquired, due to an inhibitory antibody. Analysis of ADAMTS13 activity is carried out applying tests based upon the capability in the protease to cleave common VWF multimers in vi